Author

D. Petropolis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

K. Karalis· 2 shared R. Barrile· 2 shared A. B. Roth· 1 shared A. Freimoser-Grundschober· 1 shared A. Herland· 1 shared A. M. Giusti· 1 shared A. Moisan· 1 shared A. Schneider· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

K. Karalis

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2 papers

Recent·Most cited

Human immunocompetent Organs-on-Chips platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

L. Cabon, D. Petropolis, W. Tien-Street, P. R. Ng, H. S. Grant, K. Karalis, G. A. Hamilton, J. Sam, T. Weinzierl, T. Fauti, A. Freimoser-Grundschober, J. Eckmann, C. Hage, M. Geiger, V. Micallef, , R. Barrile

The paper demonstrates that human immunocompetent Organs-on-Chips can predict safety liabilities of T-cell bispecific antibodies targeting tumor antigens.

bioRxiv · Feb 22, 2021Cancer Biology

Liver-Chip: Reproducing Human and Cross-Species Toxicities

K.-J. Jang, M. Otieno, J. Ronxhi, H.-K. Lim, L. Ewart, K. Kodella, D. Petropolis, G. Kulkarni, J. Rubins, D. Conegliano, J. Nawroth, D. Simic, W. Lam, M. Singer, E. Barale, , G. Hamilton

The paper designs Liver-Chips for rat, dog, and human to replicate species-specific liver toxicities and predict human relevance.

bioRxiv · May 15, 2019 · PreprintPharmacology & Toxicology