Author

C. Hage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Aktipis· 1 shared A. B. Roth· 1 shared A. Freimoser-Grundschober· 1 shared A. M. Giusti· 1 shared A. Moisan· 1 shared A. Schneider· 1 shared B. R. Rueda· 1 shared C. Belgur· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Aktipis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human immunocompetent Organs-on-Chips platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

L. Cabon, D. Petropolis, W. Tien-Street, P. R. Ng, H. S. Grant, K. Karalis, G. A. Hamilton, J. Sam, T. Weinzierl, T. Fauti, A. Freimoser-Grundschober, J. Eckmann, C. Hage, M. Geiger, V. Micallef, , R. Barrile

The paper demonstrates that human immunocompetent Organs-on-Chips can predict safety liabilities of T-cell bispecific antibodies targeting tumor antigens.

bioRxiv · Feb 22, 2021Cancer Biology

The kidney protects against sepsis by producing systemic uromodulin

K. LaFavers, C. Hage, V. Gaur, R. Micanovic, T. Hato, S. Khan, S. Winfree, S. Doshi, R. Moorthi, H. Twigg, X.-R. Wu, P. Dagher, E. Srour, T. M. El-Achkar

This paper identifies uromodulin (THP) as a protective factor in sepsis, showing its role in enhancing mononuclear phagocyte function and reducing mortality in mice.

bioRxiv · Jan 8, 2021Immunology

Transient Commensal Clonal Interactions Can Drive Tumor Metastasis

S. Naffar-Abu Amara, H. J. Kuiken, L. M. Selfors, T. Butler, M. L. Leung, C. T. Leung, E. P. Kuhn, T. R. Kolarova, C. Hage, K. Ganesh, R. Foster, B. R. Rueda, A. Aktipis, P. T. Spellman, T. Ince, , J. S. S. Brugge

The paper shows that transient interactions between non-tumorigenic and tumorigenic clones can drive metastasis through amphiregulin-mediated mesothelial clearance.

bioRxiv · Jan 16, 2020 · PreprintCancer Biology