Author

D. R. Neill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 2 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. E. Green· 3 shared A. A. Cox· 1 shared A. Anil· 1 shared A. Banerjee· 1 shared A. Beckett· 1 shared A. Green· 1 shared A. Kadioglu· 1 shared A. Mitchell· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

A. E. Green

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4 papers

Recent·Most cited

Identification of two distinct phylogenomic lineages and model strains for the understudied cystic fibrosis lung pathogen Burkholderia multivorans

K. M. Parfitt, A. E. Green, T. R. Connor, D. R. Neill, E. Mahenthiralingam

bioRxiv · Jan 3, 2023 · PreprintMicrobiology

Pseudomonas aeruginosa utilises host-derived polyamines to facilitate antimicrobial tolerance

C. M. Hasan, A. Green, A. A. Cox, J. White, T. Jones, C. Winstanley, A. Kadioglu, M. Wright, D. R. Neill, J. L. Fothergill

This study shows that Pseudomonas aeruginosa uses host-derived polyamines, like spermidine, to enhance antimicrobial tolerance during infection, despite reduced susceptibility in vitro.

bioRxiv · Dec 15, 2021 · PreprintMicrobiology

Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle

D. C. Badgujar, A. Anil, A. E. Green, M. V. Surve, S. Madhavan, A. Beckett, I. Prior, B. K. Godsora, S. B. Patil, P. K. More, S. Guha Sarkar, A. Mitchell, R. Banerjee, P. P. Phale, T. J. Mitchell, , A. Banerjee

This paper identifies structural changes in a non-hemolytic pneumolysin variant that disable pore formation, enabling pneumococcus to adopt an intracellular lifestyle with reduced inflammation and increased host tolerance.

PLOS Pathogens · Nov 20, 2020Peer-reviewedMicrobiology

Identification of colonisation and virulence determinants of Streptococcus pneumoniae via experimental evolution in mouse infection models

A. E. Green, D. Howarth, C. Chaguza, H. Echlin, R. F. Langendonk, C. Munro, T. E. Barton, J. C. Hinton, S. D. Bentley, J. Rosch, D. R. Neill

This study uses experimental evolution in mouse models to identify genetic factors affecting Streptococcus pneumoniae colonization and virulence.

bioRxiv · Sep 8, 2020 · PreprintMicrobiology