Author

D. S. Gerhard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

S. Meshinchi· 3 shared A. S. Gamis· 2 shared E. A. Kolb· 2 shared J. M. Guidry Auvil· 2 shared J. Zhang· 2 shared M. A. Smith· 2 shared T. A. Alonzo· 2 shared A. Califano· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

S. Meshinchi

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4 papers

Recent·Most cited

A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data

E. F. Douglass, R. J. Allaway, B. Szalai, W. Wang, T. Tian, A. Fernandez-Torras, R. Realubit, C. Karan, S. Zheng, A. Pessia, Z. Tanoli, M. Jafari, F. Wan, S. Li, Y. Xiong, , A. Califano

The paper hosts a DREAM Challenge to evaluate computational models for predicting drug polypharmacology using perturbational profile data from 32 kinase inhibitors.

bioRxiv · Dec 21, 2020Cancer Biology

Integrative genomics identifies lncRNA regulatory networks across 1,044 pediatric leukemias and extra-cranial solid tumors

A. Modi, G. Lopez, K. L. Conkrite, C. Su, T. C. Leung, S. Ramanan, E. Manduchi, M. E. Johnson, D. Cheung, S. Gadd, J. Zhang, M. A. Smith, J. M. Guidry Auvil, D. S. Gerhard, S. Meshinchi, , S. J. Diskin

The paper identifies lncRNA regulatory networks in pediatric cancers using integrated genomics data from 1,044 samples, revealing their roles in proliferation, metabolism, and DNA damage.

bioRxiv · Dec 10, 2020 · PreprintCancer Biology

Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia: A report from the TARGET initiative

N. McNeer, J. Philip, H. Geiger, R. Ries, V.-P. Lavallee, M. Walsh, M. Shah, K. Arora, A.-K. Emde, N. Robine, T. A. Alonzo, E. A. Kolb, A. S. Gamis, M. Smith, D. S. Gerhard, , A. Kentsis

The paper identifies genetic mechanisms of primary chemotherapy resistance in pediatric AML through whole-genome and transcriptome sequencing of treatment-failure cases.

bioRxiv · Nov 26, 2018Cancer Biology

Comprehensive characterization of pediatric AML reveals diverse fusion oncoproteins and age-specific mutational interactions

H. Bolouri, J. E. Farrar, T. J. Triche, R. E. Ries, E. L. Lim, T. A. Alonzo, Y. Ma, R. Moore, A. Mungall, M. A. Marra, J. Zhang, X. Ma, Y. Liu, Y. Liu, J. M. Guidry Auvil, , S. Meshinchi

This study characterizes the molecular landscape of pediatric AML, identifying age-specific mutations and fusion oncoproteins that differ from adult AML.

bioRxiv · Oct 10, 2017Cancer Biology