Dissecting PADI6 function defines oocyte cytoplasmic lattices as regulatory hubs for fundamental cellular processes
Jack P. C. Williams, Tania Auchynnikava, Afshan McCarthy, M. Teresa Bertran, Obah A. Ojarikre, Anne Weston, Daniel R. Leonce, Jessica Olsen, Kathy K. Niakan, Mark J. Skehel, James M. A. Turner, Louise J. Walport
The paper investigates PADI6's role in oocyte cytoplasmic lattices using single-cell proteomics and transcriptomics, revealing its critical scaffolding function and connections to other oocyte compartments.
bioRxiv · Feb 21, 2025 · PreprintDevelopmental Biology