Author

David Wollensak

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Fei CheniD· 2 shared Andrea Navarro TorresiD· 1 shared Anisha LaumasiD· 1 shared Anubhav SinhaiD· 1 shared Armen SaghatelyaniD· 1 shared Aviv RegeviD· 1 shared Denny SakkasiD· 1 shared Edward S. BoydeniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Fei ChenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Unified Transcriptome and Mechanics Map of the Intact Mammalian Preimplantation Embryo In Situ

Ehsan Habibi, Anubhav Sinha, Haiqian Yang, Payman Yadollahpour, Raquel Rodríguez-Aller, Yiwei Li, Lani Lee, David Wollensak, Zachary Chiang, Denny Sakkas, Edward S. Boyden, Armen Saghatelyan, Ming Guo, Aviv Regev, Fei Chen

This paper introduces UTMM, a method to simultaneously measure transcriptomes and mechanical properties in intact embryos, revealing coupling between RNA expression and intracellular compliance during early development.

bioRxiv · Feb 24, 2026 · PreprintDevelopmental Biology

Generative Design of Cell Type-Specific RNA Splicing Elements for Programmable Gene Regulation

Xi Dawn Chen, Manson Jim, Mounica Vallurupalli, Kai Cao, Andrea Navarro Torres, Jing Wesley Leong, Yifan Zhang, David Wollensak, Qiyu Gong, Jing Sun, Mehdi Borji, Gail Schor, Sofia Mrowka, Margaret Hu, Anisha Laumas, , Fei Chen

The paper introduces SPICE, a framework that uses splicing assays and generative design to create cell-specific gene regulation elements for research and therapy.

bioRxiv · Nov 5, 2025 · PreprintMolecular Biology