Author

Dirk Jäger

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Akash PatnaikiD· 1 shared Alexander T. PearsoniD· 1 shared Àlvaro Quintanal-VillalongaiD· 1 shared Amelie EchleiD· 1 shared Andrea Littbarski· 1 shared Andrew M. Hanby· 1 shared Andrew SrisuwananukorniD· 1 shared Anja WilliamsiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Akash PatnaikORCID

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Author profile →

3 papers

Recent·Most cited

Hierarchical classification of immune cell transcriptomes at population-scale

Christopher Beltz, Zekai Qiu, Leon Sadowski, Joscha A. Kraske, Anmol Aggarwal, Àlvaro Quintanal-Villalonga, Parvathy Manoj, Andrea Littbarski, Sunanjay Bajaj, Brigita Meškauskaitė, Shigeaki Umeda, Linas Mažutis, Samuel A. Rose, Joseph M. Chan, Tal Nawy, , Thomas Walle

The paper introduces Suco and Compocyte to classify immune cells from 3,965 patients, identifying new macrophage and monocyte states and T cell memory erosion in metastases.

bioRxiv · Jun 21, 2026 · PreprintBioinformatics

Image-based screens identify regulators of endogenous Dvl2 biomolecular condensates

Antonia Schubert, Florian Heigwer, Christian Scheeder, Oksana Voloshanenko, Dominique Kranz, Franziska Ragaller, Nadine Winkler, Thilo Miersch, Barbara A. Schmitt, Melanie Kuhse, Daniel Gimenes, Diana Ordoñez‐Rueda, Jennifer Schwarz, Frank Stein, Dirk Jäger, , Michael Boutros

The paper identifies regulators of Dvl2 biomolecular condensates using image-based screens and phosphoproteomics, finding CK1δ/ε inhibition blocks condensate formation and modulates Wnt signaling.

bioRxiv · Jan 11, 2025 · PreprintCell Biology

Pan-cancer image-based detection of clinically actionable genetic alterations

Jakob Nikolas Kather, Lara Rosaline Heij, Heike Irmgard Grabsch, Chiara Maria Lavinia Loeffler, Amelie Echle, Hannah Sophie Muti, Jeremias Krause, Jan Niehues, Kai A. J. Sommer, Peter Bankhead, Loes F. S. Kooreman, Jefree J. Schulte, Nicole A. Cipriani, Roman David Buelow, Peter Boor, , Tom Luedde

This paper develops a deep learning method to predict genetic alterations from histological images across multiple cancer types.

Nature Cancer · Jul 27, 2020Peer-reviewedGenetics