A family of lethal exotoxins defined by cell entry via the Attractin receptor
Raghuvir Viswanatha, Donghoon Lee, William Paul Robins, Enzo Mameli, Yanhui Hu, Ah‐Ram Kim, Yousuf Hashmi, Hiroshi Nishida, Gyan Prakash, Matthew Butnaru, L. Stirling Churchman, Stephanie Elizabeth Mohr, John J. Mekalanos, Norbert Perrimon
The paper identifies Attractin as the receptor for Nigritoxin, a Vibrio toxin, and shows that related toxins use this receptor but have distinct effector domains.
bioRxiv · Oct 8, 2025 · PreprintMicrobiology