Author

Gyan Prakash

Harvard UniversityORCID 0000-0003-4725-9178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Stirling ChurchmaniD· 3 shared Ah‐Ram KimiD· 1 shared Boryana PetrovaiD· 1 shared Claire H. Nuessmeier· 1 shared Donghoon Lee· 1 shared Enzo MameliiD· 1 shared Hiroshi NishidaiD· 1 shared Hope E. MerensiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMolecular Biology

L. Stirling ChurchmanORCID

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3 papers

Recent·Most cited

Mitochondrial RNA processing promotes translation by resolving structured precursor RNAs

Claire H. Nuessmeier, Gyan Prakash, Lisa N. Hansen, Mary Couvillion, L. Stirling Churchman

The paper shows that FASTKD4-dependent processing of mitochondrial RNA junctions is required for efficient CYB translation by removing RNA structures that hinder mitoribosome engagement.

bioRxiv · Jul 31, 2026 · PreprintMolecular Biology

A family of lethal exotoxins defined by cell entry via the Attractin receptor

Raghuvir Viswanatha, Donghoon Lee, William Paul Robins, Enzo Mameli, Yanhui Hu, Ah‐Ram Kim, Yousuf Hashmi, Hiroshi Nishida, Gyan Prakash, Matthew Butnaru, L. Stirling Churchman, Stephanie Elizabeth Mohr, John J. Mekalanos, Norbert Perrimon

The paper identifies Attractin as the receptor for Nigritoxin, a Vibrio toxin, and shows that related toxins use this receptor but have distinct effector domains.

bioRxiv · Oct 8, 2025 · PreprintMicrobiology

Genome-wide screens for mitonuclear co-regulators uncover links between compartmentalized metabolism and mitochondrial gene expression

Nicholas J. Kramer, Gyan Prakash, R. Stefan Isaac, Karine Choquet, Iliana C. Soto, Boryana Petrova, Hope E. Merens, Naama Kanarek, L. Stirling Churchman

The paper identifies genes involved in mitochondrial and nuclear gene regulation for OXPHOS complex synthesis using genome-wide screens and characterizes their roles in mitochondrial RNA abundance and mitoribosome assembly.

Nature Cell Biology · Sep 28, 2023Peer-reviewedMolecular Biology