Author

E. A. Boyle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Research Focus:polygenic risk· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Harpak· 1 shared A. K. S. Arakaki· 1 shared A. M. Joergensen· 1 shared DASL Alliance· 1 shared F. Izidro Layng· 1 shared F. Racimo· 1 shared G. Coop· 1 shared G. Ecklu-Mensah· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

A. Harpak

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Author profile →

3 papers

Recent·Most cited

Junior scientists spotlight social bonds in seminars for diversity, equity, and inclusion in STEM

E. A. Boyle, G. Goldberg, J. C. Schmok, J. Burgado, F. Izidro Layng, H. A. Grunwald, K. M. Balotin, M. S. Cuoco, K.-C. Chang, G. Ecklu-Mensah, A. K. S. Arakaki, N. Ahmed, X. Garcia Arceo, P. Jagannatha, J. Pekar, , G. W. Yeo

The paper analyzes seminar talks by junior scientists to assess how they discuss diversity, equity, and inclusion in STEM, finding common themes and intersectional identities.

bioRxiv · Dec 5, 2021Scientific Communication & Education

Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement

E. A. Boyle, W. R. Becker, H. B. Bai, J. S. Chen, J. A. Doudna, W. J. Greenleaf

The paper quantifies Cas9 binding and cleavage across diverse guide sequences, revealing sequence-specific variations in efficacy and specificity, and develops a predictive biophysical model.

bioRxiv · Sep 9, 2020Biochemistry

Reduced signal for polygenic adaptation of height in UK Biobank

J. J. Berg, A. Harpak, N. Sinnott-Armstrong, A. M. Joergensen, H. Mostafavi, Y. Field, E. A. Boyle, X. Zhang, F. Racimo, J. K. Pritchard, G. Coop

The paper analyzes polygenic height scores from UK Biobank and finds reduced signals of selection compared to previous studies, suggesting potential issues with population stratification correction.

bioRxiv · Dec 10, 2018Evolutionary Biology