Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.
J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle
The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.
bioRxiv · Dec 12, 2021Immunology