Author

D. Andrew

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:clustering· 1

Frequent Co-Authors

M. J. Boyle· 4 shared B. Barber· 3 shared J. A. Lopez· 3 shared A. SheelaNair· 2 shared C. Engwerda· 2 shared J. Loughland· 2 shared J. R. Loughland· 2 shared J. S. McCarthy· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

M. J. Boyle

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Heterogeneity of the human immune response to malaria infection and vaccination driven by latent cytomegalovirus infection

R. Mukhiya, W. A. Fleischmann, J. R. Loughland, J.-A. Chan, F. de Labastida Rivera, D. Andrew, J. G. Beeson, J. S. McCarthy, B. Barber, J. A. Lopez, C. Engwerda, R. Thomson-Luque, M. J. Boyle

This study shows that latent cytomegalovirus infection reduces antibody responses to malaria infection and vaccination by altering Tfh cell subsets and their activation.

bioRxiv · Apr 28, 2024Immunology

Malaria drives unique regulatory responses across multiple immune cell subsets

N. L. Dooley, Z. Pava, J. R. Loughland, J. Hamelink, K. Berry, D. Andrew, M. S. F. Soon, A. SheelaNair, K. A. Piera, T. William, B. Barber, M. J. Grigg, C. R. Engwerda, J. A. Lopez, N. M. Anstey, M. J. Boyle

The paper analyzes single-cell RNA sequencing data from malaria patients to identify immunoregulatory responses in specific immune cell subsets during infection and recovery.

bioRxiv · Nov 16, 2022 · PreprintImmunology

STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria

Y. Wang, F. Rivera, C. Edwards, T. Frame, J. A. Engel, L. Bukali, J. Na, S. Ng, D. Corvino, M. Montes de Oca, P. Bunn, M. Soon, D. Andrew, J. Loughland, F. Amante, , C. Engwerda

This study shows STING activation promotes Tr1 cell development during malaria by enhancing IFNB gene transcription and modulates this pathway with ruxolitinib.

bioRxiv · Sep 4, 2022Immunology

Human anti-ACE2 monoclonal antibodies as pan-sarbecovirus prophylactic agents

F. Zhang, J. Jenkins, R. V. H. de Carvalho, S. Nakandakari-Higa, T. Chen, M. E. Abernathy, E. Nyakatura, D. Andrew, I. V. Lebedeva, I. C. Lorenz, H.- H. Hoffmann, C. M. Rice, G. D. Victora, C. O. Barnes, T. Hatziioannou, P. D. Bieniasz

The paper develops human monoclonal antibodies targeting the ACE2 receptor to block infection by SARS-CoV-2 and related sarbecoviruses, showing broad efficacy against variants and no adverse effects on ACE2 function.

bioRxiv · Aug 24, 2022 · PreprintMicrobiology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology