Author

A. SheelaNair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

M. J. Boyle· 3 shared A. Haque· 2 shared D. Andrew· 2 shared H. J. Lee· 2 shared J. A. Engel· 2 shared J. Loughland· 2 shared J.-A. Chan· 2 shared M. Hogarth· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

M. J. Boyle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Malaria drives unique regulatory responses across multiple immune cell subsets

N. L. Dooley, Z. Pava, J. R. Loughland, J. Hamelink, K. Berry, D. Andrew, M. S. F. Soon, A. SheelaNair, K. A. Piera, T. William, B. Barber, M. J. Grigg, C. R. Engwerda, J. A. Lopez, N. M. Anstey, M. J. Boyle

The paper analyzes single-cell RNA sequencing data from malaria patients to identify immunoregulatory responses in specific immune cell subsets during infection and recovery.

bioRxiv · Nov 16, 2022 · PreprintImmunology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology

Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites

L. I. M. Lansink, J. A. Engel, H. J. Lee, M. S. F. Soon, C. G. Williams, A. SheelaNair, C. P. S. Pernold, P. Laohamonthonkul, J. Akter, T. Stoll, M. M. Hill, A. M. Talman, A. J. C. Russell, M. Lawniczak, M. P. Davenport, , A. Haque

The paper shows that systemic host inflammation slows malaria parasite maturation and alters their transcriptomic profile in vivo.

bioRxiv · Aug 18, 2021Microbiology

Th2-like T-follicular helper cells promote functional antibody production during Plasmodium falciparum infection

J.-A. Chan, F. de Labastida Rivera, J. Loughland, J. A. Engel, H. J. Lee, A. SheelaNair, B. Wines, F. Amante, L. Webb, P. Mukhopadhyay, A.-M. Patch, M. Hogarth, J. A. Beeson, J. McCarthy, A. Haque, , M. J. Boyle

The paper identifies Th2-like T-follicular helper cells as key drivers of functional antibody production during Plasmodium falciparum infection, suggesting they are targets for improved malaria vaccines.

bioRxiv · May 18, 2020Immunology