Author

G. Dorsey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Ecology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2

Frequent Co-Authors

B. Greenhouse· 4 shared M. Kamya· 4 shared F. Nankya· 3 shared J. Rek· 3 shared K. Musinguzi· 3 shared M. E. Feeney· 3 shared M. R. Kamya· 3 shared A. Kakuru· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersImmunology

B. Greenhouse

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Distinct transcriptional profiles of maternal and fetal placental macrophages at term are associated with gravidity

N. Ozarslan, J. F. Robinson, S. Buarpung, M. Y. Kim, M. R. Ansbro, J. Akram, D. J. Montoya, M. R. Kamya, A. Kakuru, G. Dorsey, P. J. Rosenthal, G. Cheng, M. E. Feeney, S. J. Fisher, S. L. Gaw

The paper compares transcriptional profiles of maternal and fetal placental macrophages in term pregnancies, finding distinct gene expression patterns linked to gravidity.

bioRxiv · Sep 25, 2023 · PreprintImmunology

Disease Tolerance Acquired Through Repeated Plasmodium Infection Involves Epigenetic Reprogramming of Innate Immune Cells

J. Nideffer, M. Ty, M. Donato, J. Rek, R. Kajubi, X. Ji, H. Maecker, F. Nankya, K. Musinguzi, K. Press, B. Greenhouse, M. Kamya, M. E. Feeney, G. Dorsey, P. Utz, , P. Jagannathan

The paper shows that repeated Plasmodium infection leads to epigenetic changes in innate immune cells, which suppress inflammation and confer long-term disease tolerance in Ugandan children.

bioRxiv · Apr 19, 2023 · PreprintImmunology

In Utero Activation of NK Cells in Congenital CMV Infection

A. V. Vaaben, J. Levan, C. B. T. Nguyen, P. C. Callaway, M. Prahl, L. Warrier, F. Nankya, K. Musinguzi, A. Kakuru, M. K. Muhindo, G. Dorsey, M. R. Kamya, M. E. Feeney

The paper examines NK cell activation in congenital CMV infection by analyzing cord blood samples from infected and uninfected newborns, finding increased cytotoxicity and maturation in infected infants.

bioRxiv · Apr 4, 2022Immunology

The durability of long-lasting insecticidal nets treated with and without piperonyl butoxide (PBO) in Uganda.

F. Mechan, A. Katureebe, V. Tuhaise, M. Mugote, A. Oruni, I. Onyige, K. Bumali, J. Thornton, K. Maxwell, M. Kyohere, M. R. Kamya, P. Mutungi, S. P. Kigozi, A. Yeka, J. Opigo, , A. Lynd

This study compares the durability and bioefficacy of PBO-treated and pyrethroid-only LLINs in Uganda, finding that PBO content declines over time, reducing bioefficacy against resistant mosquitoes.

bioRxiv · Feb 17, 2022 · PreprintZoology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology

Impact of a rapid decline in malaria transmission on antimalarial IgG subclasses and avidity

I. Ssewanyana, J. Rek, I. Rodriguez, L. Wu, E. Arinaitwe, J. Nankabirwa, J. Beeson, H. Mayanja- Kizza, P. Rosenthal, G. Dorsey, M. Kamya, C. Drakeley, B. Greenhouse, K. K. Tetteh

The paper examines how malaria transmission decline affects antimalarial IgG subclasses and avidity in Ugandans, finding age-related changes in IgG decay, subclass ratios, and avidity dynamics.

bioRxiv · Jun 26, 2020Immunology

Heterogeneous exposure and hotspots for malaria vectors at three study sites in Uganda

S. Y. Kang, K. E. Battle, H. S. Gibson, L. V. Cooper, K. Maxwell, M. Kamya, S. Lindsay, G. Dorsey, B. Greenhouse, I. Rodriguez-Barraquer, R. C. Reiner, D. L. Smith, D. Bisanzio

This study quantifies household and spatial variation in malaria vector exposure using Bayesian modeling in three Ugandan sites, identifying hotspots linked to environmental factors and seasonal changes.

bioRxiv · Apr 11, 2018Ecology