Author

E. B. Sobolik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

A. L. Greninger· 2 shared C. M. Lieber· 2 shared H.-J. Kang· 2 shared J.-J. Yoon· 2 shared M. G. Natchus· 2 shared N. A. P. Lieberman· 2 shared R. Cox· 2 shared R. K. Plemper· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. L. Greninger

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2 papers

Recent·Most cited

Influenza A virus resistance to 4-fluorouridine coincides with viral attenuation in vitro and in vivo

C. M. Lieber, H.-J. Kang, M. Aggarwal, N. A. P. Lieberman, E. B. Sobolik, J.-J. Yoon, M. G. Natchus, R. Cox, A. L. Greninger, R. K. Plemper

This study identifies mutations conferring resistance to 4-fluorouridine in influenza viruses and shows that resistant variants are attenuated in vivo and can be overcome by higher drug doses.

bioRxiv · Oct 20, 2023 · PreprintMicrobiology

Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets

R. K. Plemper, R. Cox, J. D. Wolf, N. A. P. Lieberman, C. M. Lieber, H.-J. Kang, Z. M. Sticher, J.-J. Yoon, M. K. Andrews, M. Govindarajan, R. E. Krueger, E. B. Sobolik, M. G. Natchus, A. Gewirtz, R. deSwart, , A. L. Greninger

This study shows that prior respiratory virus infections worsen measles severity in ferrets and that antiviral treatment can mitigate immune amnesia and disease outcomes regardless of treatment timing.

bioRxiv · Sep 1, 2023Microbiology