Author

M. Govindarajan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

M. G. Natchus· 2 shared R. Cox· 2 shared R. K. Plemper· 2 shared R. Khokha· 2 shared T. Kislinger· 2 shared A. Gewirtz· 1 shared A. Khoo· 1 shared A. Kolykhalov· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

M. G. Natchus

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Droplet based low input proteomic platform for rare cell populations

M. Waas, A. Khoo, P. Tharmapalan, C. W. McCloskey, M. Govindarajan, B. Zhang, S. Khan, P. Waterhouse, R. Khokha, T. Kislinger

DROPPS enables high-fidelity proteomic profiling of rare cell populations with low input, revealing CD36 as a marker of progenitor capacity in mammary basal cells.

bioRxiv · Sep 11, 2023 · PreprintBiochemistry

Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets

R. K. Plemper, R. Cox, J. D. Wolf, N. A. P. Lieberman, C. M. Lieber, H.-J. Kang, Z. M. Sticher, J.-J. Yoon, M. K. Andrews, M. Govindarajan, R. E. Krueger, E. B. Sobolik, M. G. Natchus, A. Gewirtz, R. deSwart, , A. L. Greninger

This study shows that prior respiratory virus infections worsen measles severity in ferrets and that antiviral treatment can mitigate immune amnesia and disease outcomes regardless of treatment timing.

bioRxiv · Sep 1, 2023Microbiology

Glycoproteomics Identifies Plexin-B3 as Targetable Cell Surface Protein Required for Growth and Invasion of Triple Negative Breast Cancer Cells

L. Kuhlmann, M. Govindarajan, S. Mejia-Guerrero, V. Ignatchenko, L. Y. Liu, B. T. Grunwald, J. Cruickshank, H. Berman, R. Khokha, T. Kislinger

This study identifies Plexin-B3 as a cell surface protein essential for TNBC growth and invasion, using glycoproteomics and functional validation.

bioRxiv · Jun 1, 2022 · PreprintCancer Biology

Therapeutic Targeting of Measles Virus Polymerase with ERDRP-0519Suppresses All RNA Synthesis Activity

R. Cox, J. Sourimant, M. Govindarajan, M. G. Natchus, R. K. Plemper

This paper characterizes ERDRP-0519, a small molecule inhibitor of measles virus polymerase, showing it blocks all RNA synthesis activity through a unique mechanism.

bioRxiv · Sep 23, 2020Microbiology