Hepatic IRE1 Protects Against Septic Cardiac Failure
M. Li, R. R. Berton, Q. Qian, J. A. Maschek, B. Chen, E. Barroso, A. Rauckhorst, T. S. Griffith, E. B. Taylor, J. E. Cox, V. P. Badovinac, G. S. Hotamisligil, L.-s. Song, L. Yang
This study shows that hepatic IRE1 protects against septic cardiac failure by maintaining lipid metabolic balance, independent of inflammation.
bioRxiv · Mar 14, 2023 · PreprintPathology