Author

A. Rauckhorst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metabolomics· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. B. Taylor· 3 shared A. R. Jackson· 1 shared A. Simoni· 1 shared B. Chen· 1 shared B. G. Allen· 1 shared D. R. Spitz· 1 shared D. Zepeda-Orozco· 1 shared E. Barroso· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiochemistry

E. B. Taylor

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

3-hydroxykynurenine is a ROS-inducing cytotoxic tryptophan metabolite that disrupts the TCA cycle

J. L. Buchanan, A. Rauckhorst, E. B. Taylor

This study identifies 3-hydroxykynurenine as a cytotoxic tryptophan metabolite that disrupts the TCA cycle and induces ROS-mediated apoptosis in colon cancer cells.

bioRxiv · Jul 10, 2023 · PreprintBiochemistry

Hepatic IRE1 Protects Against Septic Cardiac Failure

M. Li, R. R. Berton, Q. Qian, J. A. Maschek, B. Chen, E. Barroso, A. Rauckhorst, T. S. Griffith, E. B. Taylor, J. E. Cox, V. P. Badovinac, G. S. Hotamisligil, L.-s. Song, L. Yang

This study shows that hepatic IRE1 protects against septic cardiac failure by maintaining lipid metabolic balance, independent of inflammation.

bioRxiv · Mar 14, 2023 · PreprintPathology

Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury

A. Rauckhorst, G. V. Martinez, G. M. Andrade, H. Wen, J. Y. Kim, A. Simoni, K. A. Mapuskar, P. Rastogi, E. J. Steinbach, M. L. McCormick, B. G. Allen, A. R. Jackson, N. S. Pabla, M. C. Coleman, D. R. Spitz, , D. Zepeda-Orozco

The paper shows that reducing mitochondrial pyruvate carrier activity in kidney tubular cells protects against acute kidney injury by enhancing redox defenses and survival.

bioRxiv · Jan 31, 2023Biochemistry