Author

E. Bernal-Mizrachi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

F. L. M. Pecanha· 2 shared J. P. Werneck de Castro· 2 shared A. Bautista· 1 shared A. Lin· 1 shared A. T. Franco· 1 shared B. Gablaski· 1 shared B. Lourenconi· 1 shared C. Cras-Meneur· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPhysiology

F. L. M. Pecanha

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Author profile →

4 papers

Recent·Most cited

Defining the in vivo role of mTORC1 in thyrocytes by studying the TSC2 conditional knockout mouse model

C. L. Rossetti, B. Lourenconi, F. L. M. Pecanha, A. T. Franco, V. Nose, J. Lew, E. Carneiro, E. Bernal-Mizrachi, J. P. Werneck de Castro

This study uses a TSC2 conditional knockout mouse model to show that mTORC1 activation in thyrocytes inhibits thyroid hormone biosynthesis, promotes growth, and leads to thyroid tumors.

bioRxiv · Nov 1, 2023 · PreprintPhysiology

TGS1: a novel regulator of β-cell mass and function

M. Blandino-Rosano, P. Romaguera-Llacer, A. Lin, J. K. Reddy, E. Bernal-Mizrachi

This study identifies TGS1 as a regulator of β-cell mass and function, showing its role in glucose homeostasis and response to high-fat diet through mechanisms involving ER stress and cell cycle regulation.

bioRxiv · Sep 20, 2021 · PreprintCell Biology

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

S. Skovso, E. Panzhinskiy, J. Kolic, H. H. Cen, D. A. Dionne, X.-Q. Dai, R. B. Sharma, L. Elghazi, C. E. Ellis, K. Faulkner, S. A. M. Marcil, P. Overby, N. Noursadeghi, D. Hutchinson, X. Hu, , J. D. Johnson

This study shows that deleting the insulin receptor in beta-cells improves glucose tolerance in some mice but not others, depending on age and diet.

bioRxiv · Oct 15, 2020Physiology

Is there a role for the RNA-binding protein LARP1 in β-cells?

J. P. Werneck de Castro, F. L. M. Pecanha, D. H. Silvestre, E. Bernal-Mizrachi

This study investigates the role of LARP1 in β-cells, finding it is the most abundant LARP in mouse islets and human β-cells, and its absence does not affect glucose homeostasis but may impair glucose tolerance with long-term BCAA diet.

bioRxiv · Sep 3, 2020 · PreprintPhysiology