Author

J. Kolic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

J. D. Johnson· 4 shared E. Panzhinskiy· 3 shared H. H. Cen· 3 shared P. Overby· 3 shared P. E. Macdonald· 2 shared S. Skovso· 2 shared X.-Q. Dai· 2 shared A. Bautista· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersCell Biology

J. D. Johnson

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Author profile →

4 papers

Recent·Most cited

β-Hydroxybutyrate promotes basal insulin secretion while decreasing glucagon secretion in mouse and human islets.

R. Banerjee, Y. Zhu, G. P. Brownrigg, R. Moravcova, J. C. Rogalski, L. Foster, J. D. Johnson, J. Kolic

This study shows that β-hydroxybutyrate (βHB) increases insulin secretion and decreases glucagon secretion in human and mouse islets at physiological glucose concentrations.

bioRxiv · Feb 27, 2024Cell Biology

Pharmacological or genetic inhibition of Scn9a protects human and mouse beta cells while dampening insulin secretion in type 1 diabetes

P. Overby, A. G. Gordon, X.-Q. Dai, N. S. Nahirney, S. Provenzano, W. G. Sun, Y. Xia, J. A. Zhang, E. Panzhinskiy, C. M. J. Chu, H. H. Cen, S. Skovso, J. Kolic, A. G. Edwards, P. E. Macdonald, J. D. Johnson

This study shows that inhibiting Scn9a protects beta cells in type 1 diabetes by reducing excitability and improving survival, while also dampening insulin secretion.

bioRxiv · Jun 11, 2023 · PreprintPhysiology

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

S. Skovso, E. Panzhinskiy, J. Kolic, H. H. Cen, D. A. Dionne, X.-Q. Dai, R. B. Sharma, L. Elghazi, C. E. Ellis, K. Faulkner, S. A. M. Marcil, P. Overby, N. Noursadeghi, D. Hutchinson, X. Hu, , J. D. Johnson

This study shows that deleting the insulin receptor in beta-cells improves glucose tolerance in some mice but not others, depending on age and diet.

bioRxiv · Oct 15, 2020Physiology

Differential effects of voclosporin and tacrolimus on insulin secretion from human islets

J. Kolic, L. Beet, P. Overby, H. H. Cen, E. Panzhinskiy, D. R. Ure, J. L. Cross, R. B. Huizinga, J. D. Johnson

This study compares the effects of voclosporin and tacrolimus on insulin secretion from human islets, finding that tacrolimus impairs insulin secretion while voclosporin does not.

bioRxiv · Apr 30, 2020Cell Biology