E. Hernandez

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

The paper develops a computational pipeline combining Rosetta and cryo-EM to analyze ACE2 receptor traps' binding to SARS-CoV-2 variants, showing high affinity and neutralization capabilities against Omicron and Delta.

The fluorescence-activating and absorption-shifting tag (FAST) enables live-cell fluorescence imaging of Methanococcus maripaludis

The paper introduces FAST, a fluorescent tag that enables live-cell imaging of Methanococcus maripaludis under anoxic conditions, demonstrating its use for protein analysis and interactions.

The fruit fly Anastrepha obliqua harbors three kingdoms of life in its intestinal tract.

This study identifies bacterial, fungal, and archaeal communities in the gut of Anastrepha obliqua, finding higher microbial diversity in wild flies compared to lab-reared ones.

Essential role of hyperacetylated microtubules in innate immunity escape orchestrated by the EBV-encoded BHRF1 protein

This study shows that EBV's BHRF1 protein induces microtubule hyperacetylation to form mito-aggresomes, blocking IFN signaling and promoting viral survival.

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

The paper uses cryo-EM and AlphaFold2 to determine the structure of SARS-CoV-2 Nsp2, revealing its zinc-binding site and potential interactions with host proteins.

Exposure to parasitic protists and helminths changes the intestinal community structure of bacterial microbiota but not of eukaryotes in a cohort of mother-child binomial from a semi-rural setting in Mexico

This study examines how exposure to intestinal parasites affects bacterial and eukaryotic microbiota in a mother-child cohort in Mexico, finding significant bacterial community changes but not eukaryotic ones.

IFN-γ induces epithelial-to-mesenchymal transition of cancer cells via an unique microRNA processing

This study shows IFN-γ induces EMT in cancer cells by promoting IFIT5-mediated degradation of suppressive miRNAs, enhancing invasiveness and metastasis.