Author

C.-J. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 2 Bioengineering· 1 Biophysics· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:development & morphogenesis· 4 Approach:experimental assay· 4 Approach:statistical model· 4 Assay:imaging· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2

Frequent Co-Authors

E. C. Lai· 2 shared J. Vedanayagam· 2 shared R. P. Mecham· 2 shared A. A. Arbini· 1 shared A. Dang· 1 shared A. Hallas-Potts· 1 shared A. J. El Haj· 1 shared A. K. Ghag· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersEvolutionary Biology

E. C. Lai

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Multiphoton imaging of glucose, galactose, and fructose-induced formation of fluorescent advanced glycation end products in tissues

C.-J. Lin, S. I. Mondal, S.-L. Lee, J.-W. Kang, P. T. So, C.-Y. Dong

This study uses multiphoton microscopy to compare the formation of fluorescent AGEs in different porcine tissues exposed to glucose, galactose, and fructose, finding that fructose induces the highest glycation rate and collagen is a more sensitive target.

bioRxiv · Jan 4, 2023 · PreprintBiophysics

Endogenous RNAi silences a burgeoning sex chromosome arms race

J. Vedanayagam, C.-J. Lin, R. Papareddy, M. D. Nodine, A. S. Flynt, J. Wen, E. C. Lai

This study shows endogenous RNAi suppresses X-linked meiotic drive loci in Drosophila simulans, revealing rapid evolution of hpRNA-target interactions and their role in sex chromosome conflict.

bioRxiv · Aug 22, 2022 · PreprintEvolutionary Biology

Polarized localization of phosphatidylserine in endothelium regulates Kir2.1

C. A. Ruddiman, R. Peckham, M. A. Luse, Y. L. A. Chen, M. Kuppusamy, B. Corliss, P. J. Hall, C.-J. Lin, S. M. Peirce, S. K. Sonkusare, R. P. Mecham, J. E. Wagenseil, B. E. Isakson

The paper shows phosphatidylserine (PS) localizes to myoendothelial junctions (MEJs) in endothelium, inhibiting PIP2-mediated Kir2.1 activation to regulate vascular diameter.

bioRxiv · Aug 1, 2022Physiology

Progerin triggers a phenotypic switch in vascular smooth muscle cells that causes replication stress and an aging-associated secretory signature

N. Coll-Bonfill, U. Mahajan, C.-J. Lin, R. P. Mecham, S. Gonzalo

This study shows that progerin induces a phenotypic switch in vascular smooth muscle cells, causing replication stress and an aging-associated secretory signature, contributing to vascular stiffness in progeria.

bioRxiv · Feb 5, 2022 · PreprintCell Biology

Red queen's race: rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressors

J. Vedanayagam, C.-J. Lin, E. C. Lai

The paper traces the evolutionary dynamics of meiotic drive factors and their hpRNA suppressors in Drosophila species, revealing rapid gene amplification and genomic conflicts.

bioRxiv · Aug 5, 2021Evolutionary Biology

Remote spatially variant debiased profiling of cell and tissue mechanical properties

J. H. Mason, L. Luo, Y. Reinwald, M. Taffetani, A. Hallas-Potts, C. S. Herrington, V. Srsen, C.-J. Lin, I. A. Barroso, Z. Zhang, Z. Zhang, A. K. Ghag, Y. Yang, S. Waters, A. J. El Haj, P. Bagnaninchi

This paper introduces a noninvasive optical coherence elastography method to profile cell and tissue mechanical properties using ambient vibrations, validated in silico and in vitro.

bioRxiv · May 12, 2021 · PreprintBioengineering

Correlation between cancer stem cells, inflammation and malignant transformation in a DEN-induced model of hepatic carcinogenesis

C.-C. Wu, C.-J. Lin, K.-K. Kuo, W.-T. Chen, C.-G. Ker, C.-Y. Chai, H.-P. Tsai, S.-F. Yang

bioRxiv · Apr 17, 2020 · PreprintCancer Biology

IFN-γ induces epithelial-to-mesenchymal transition of cancer cells via an unique microRNA processing

J.-T. Hsieh, U.-G. Lo, R.-C. Pong, D. Yang, L. Gandee, E. Hernandez, A. Dang, C.-J. Lin, J. Santoyo, S.-H. M. Ma, R. Sonavane, J. Huang, S.-F. Tseng, L. Moro, A. A. Arbini, , H. Lin

This study shows IFN-γ induces EMT in cancer cells by promoting IFIT5-mediated degradation of suppressive miRNAs, enhancing invasiveness and metastasis.

bioRxiv · Jun 25, 2018 · PreprintCancer Biology