Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway
D. Hershkovitz, E. J. Chen, A. W. Ensminger, A. S. Dugan, K. T. Conway, A. C. Joyce, G. Segal, R. R. Isberg
The paper identifies LegA7 as a cysteine protease in L. pneumophila that regulates MAPK pathway activation through conserved residues and ankyrin repeats.
bioRxiv · Mar 17, 2024 · PreprintMicrobiology