Author

R. A. Greenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2

Frequent Co-Authors

A. J. Minn· 2 shared D. E. Discher· 2 shared J. Irianto· 2 shared S. M. Harding· 2 shared W. Li· 2 shared A. Kam· 1 shared C. R. Pfeifer· 1 shared D. Liu· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. J. Minn

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

P. Verma, Y. Zhou, Z. Cao, P. Deraska, M. Deb, E. Arai, W. Li, Y. Shao, Y. Li, L. Puentes, s. patankar, R. H. Mach, R. B. Faryabi, J. Shi, R. A. Greenberg

This study identifies ALC1 as a key determinant of PARPi toxicity in HR-deficient cells by linking PARP-dependent chromatin remodeling to PARPi response.

bioRxiv · Dec 16, 2020Cancer Biology

Cell cycle checkpoints cooperate to suppress DNA and RNA associated molecular pattern recognition and anti-tumor immune responses

R. A. Greenberg, J. Chen, S. M. Harding, N. Ramakrishnan, L. Tian, J. Benci, W. Li, A. J. Minn, I. Asangani

The paper shows that disrupting cell cycle checkpoints can restore DNA damage-induced inflammation and anti-tumor immune responses in cancer cells.

bioRxiv · Jun 24, 2020Cell Biology

Behavioural mechanisms underlying the evolution of cooperative burrowing in Peromyscus mice

N. L. Bedford, J. N. Weber, W. Tong, F. Baier, A. Kam, R. A. Greenberg, H. E. Hoekstra

The paper investigates how Peromyscus mice adapt their burrowing behavior when digging individually versus with partners, finding that cooperative digging results in longer burrows due to increased social cohesion in opposite-sex pairs.

bioRxiv · Aug 20, 2019Evolutionary Biology

Liquid condensation drives telomere clustering during ALT

H. Zhang, M. Liu, R. Dilley, D. M. Chenoweth, R. A. Greenberg, M. A. Lampson

The paper shows that APBs function as liquid condensates that cluster telomeres through liquid properties, supporting the ALT pathway in telomerase-free cancer cells.

bioRxiv · May 9, 2019 · PreprintCancer Biology

Rescue of DNA damage in cells after constricted migration reveals bimodal mechano-regulation of cell cycle

Y. Xia, C. R. Pfeifer, K. Zhu, J. Irianto, D. Liu, K. Pannell, E. J. Chen, L. J. Dooling, R. A. Greenberg, D. E. Discher

The paper investigates DNA damage and cell cycle effects during constricted cell migration, finding a bimodal relationship between DNA damage and cell cycle regulation.

bioRxiv · Dec 30, 2018Cell Biology

Mitotic progression following DNA damage enables pattern recognition within micronuclei

S. M. Harding, J. L. Benci, J. Irianto, D. E. Discher, A. J. Minn, R. A. Greenberg

The paper shows that mitotic progression after DNA damage forms micronuclei, which activate inflammatory signaling and are critical for abscopal tumor regression in combination with immune checkpoint blockade.

bioRxiv · Jun 27, 2017Cancer Biology