Author

E. J. Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. C. Stefan· 1 shared A. H. Corbett· 1 shared A. L. Hong· 1 shared C. Hastings· 1 shared C. Y. Jones· 1 shared D. R. Withers· 1 shared D. Sosnowska· 1 shared D. V. Fawwal· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. C. Stefan

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3 papers

Recent·Most cited

Histone H3 E50K mutation confers oncogenic activity and supports an EMT phenotype

K. Sad, C. Y. Jones, D. V. Fawwal, E. J. Hill, K. Skinner, S. Lustenberger, R. S. Lee, S. R. Elayavalli, J. Farhi, L. D. Lemon, M. B. Fasken, A. L. Hong, S. A. Sloan, A. H. Corbett, J. M. Spangle

This paper shows that the H3E50K mutation in histone H3 promotes oncogenic activity by enhancing cell migration, invasion, and epithelial-mesenchymal transition.

bioRxiv · Oct 11, 2023 · PreprintCancer Biology

Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression

J. W. Opzoomer, J. E. Anstee, I. Dean, E. J. Hill, I. Bouybayoune, J. Caron, T. Muliaditan, P. Gordon, D. Sosnowska, R. Nuamah, S. E. Pinder, T. Ng, F. Dazzi, S. Kordasti, D. R. Withers, , J. N. Arnold

This study identifies Lyve-1+ tumor-associated macrophages that support tumor growth by maintaining a pro-angiogenic perivascular niche through platelet-derived growth factor-CC-dependent expansion of mesenchymal cells.

bioRxiv · Oct 30, 2020Cancer Biology

Fluorescence assay for simultaneous quantification of CFTR ion-channel function and plasma membrane proximity

S. Prins, E. Langron, C. Hastings, E. J. Hill, A. C. Stefan, L. D. Griffin, P. Vergani

This paper introduces a fluorescence assay to simultaneously measure CFTR ion-channel function and membrane proximity, validating it with published data and drug treatments.

bioRxiv · May 5, 2020Pharmacology & Toxicology