Author

E. L. de Graaf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Ressa· 2 shared G. Vidarsson· 2 shared M. Wuhrer· 2 shared A. E. H. Bentlage· 1 shared A. H. de Ru· 1 shared A. P. J. Vlaar· 1 shared Amsterdam UMC COVID-19 biobank study group· 1 shared C. A. M. Koeleman· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

A. Ressa

Author profile →

4 papers

Recent·Most cited

Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies

D. O. Debets, E. L. de Graaf, M. C. Liefaard, G. S. Sonke, E. Lips, A. Ressa, M. Altelaar

This study uses kinase activity profiling in HER2+ breast cancer biopsies to predict treatment outcomes and identify resistance mechanisms.

bioRxiv · Sep 23, 2022Cancer Biology

Novel kinome profiling technology reveals drug treatment is patient and 2D/3D model dependent in GBM

F. Fabro, N. M. Kannegieter, E. L. de Graaf, K. Queiroz, M. L. M. Lamfers, A. Ressa, S. Leenstra

This study uses a novel kinase profiling platform to show drug efficacy and resistance in glioblastoma vary by patient and 2D/3D model.

bioRxiv · Jul 22, 2022Cancer Biology

Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19

M. D. Larsen, E. L. de Graaf, M. E. Sonneveld, H. R. Plomp, F. Linty, R. Visser, M. Brinkhaus, T. Sustic, S. W. deTaeye, A. E. H. Bentlage, J. Nouta, S. Natunen, C. A. M. Koeleman, S. Sainio, N. A. Kootstra, , G. Vidarsson

The paper shows that afucosylated IgG responses are common in enveloped virus infections and are more severe in COVID-19, with implications for immune response and pathology.

bioRxiv · May 18, 2020Immunology

Site-specific glycosylation mapping of Fc gamma receptor IIIb from neutrophils of health donors

I. Wojcik, T. Senard, E. L. de Graaf, G. M. Janssen, A. H. de Ru, Y. Mohammed, P. A. van Veelen, G. Vidarsson, M. Wuhrer, D. Falck

This study maps glycosylation sites of Fc gamma receptor IIIb from neutrophils using LC-MS/MS and identifies donor allotype differences.

bioRxiv · Apr 29, 2020Immunology