Author

E. L. Sedlacek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. S. Kennedy· 1 shared B. P. Riesenberg· 1 shared E. G. Hunt· 1 shared E. J. Gandy· 1 shared J. E. Thaxton· 1 shared J. J. Milner· 1 shared J. M. Green· 1 shared J. Modliszewski· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. S. Kennedy

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1 paper

Recent·Most cited

Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

B. P. Riesenberg, E. J. Gandy, A. S. Kennedy, E. G. Hunt, K. E. Hurst, E. L. Sedlacek, P. Gao, M. J. Emanuele, J. Modliszewski, J. M. Green, J. J. Milner, L. Wiseman, J. E. Thaxton

This study shows that enhancing the adaptive IRE1 UPR pathway in T cells improves tumor control by reducing mitochondrial toxicity and chronic ER stress.

bioRxiv · Nov 16, 2023 · PreprintImmunology