Author

E. Nola

Josep Carreras Leukaemia Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Crespo· 1 shared A. Martin Montalvo· 1 shared A. Rojas· 1 shared Aleksey LazarenkoviD· 1 shared Alfonso ValenciaiD· 1 shared Alvaro Alcalde-MerinoiD· 1 shared Andrea Nieto-AlisedaiD· 1 shared Andrei L. OkorokoviD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Crespo

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response

François Serra, Andrea Nieto-Aliseda, Lucía Fanlo, Llorenç Rovirosa, Mónica Cabrera-Pasadas, Aleksey Lazarenkov, Blanca Urmeneta, Alvaro Alcalde-Merino, E. Nola, Andrei L. Okorokov, Peter Fraser, Mariona Graupera, Sandra D. Castillo, José Luis Sardina, Alfonso Valencia, Biola M. Javierre

This study shows p53 rapidly changes 3D chromatin structure to regulate gene transcription, identifying 340 new direct target genes.

Nature Communications · Apr 1, 2024Peer-reviewedGenomics

LRH-1/NR5A2 regulates the PTGS2-PGE2-PTGER1 signalling axis contributing to islet survival and antidiabetic actions of the agonist BL001

E. Martin Vazquez, N. Cobo_Vuilleumier, R. Araujo Legido, E. Nola, L. Lopez Bermudo, A. Crespo, S. Y. Romero-Zerbo, M. Garcia-Fernandez, A. Martin Montalvo, A. Rojas, V. Comaills, F. J. Bermudez-Silva, M. Gannon, F. Martin, P. I. Lorenzo, B. R. Gauthier

This study identifies BL001's mechanism of action through LRH-1/NR5A2 activation, showing it protects beta cells via the PTGS2-PGE2-PTGER1 signalling pathway.

bioRxiv · Nov 2, 2021 · PreprintPhysiology