Andrei L. Okorokov

This study shows p53 rapidly changes 3D chromatin structure to regulate gene transcription, identifying 340 new direct target genes.

The paper identifies how the FAAH-OUT lncRNA regulates FAAH expression through DNA methylation and enhancer activity, linking it to pain insensitivity.

This study shows that Nav1.7 from sensory neurons affects dorsal horn neuron excitability, with functional effects not predicted by mRNA levels.

The paper shows that CRISPR interference at the FAAH-OUT region reduces FAAH expression, supporting its role in regulating FAAH and suggesting therapeutic potential.