Author

E. R. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Horak· 1 shared A. J. Lusis· 1 shared A. L. Brown· 1 shared A. Soliman· 1 shared C. Pan· 1 shared D. S. Allende· 1 shared E. Jiang· 1 shared G. Luo· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. J. Horak

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Author profile →

2 papers

Recent·Most cited

A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis

G. Luo, H. Kumar, K. Alridge, S. Rieger, E. Jiang, E. R. Chan, A. Soliman, H. Mahdi, J. J. Letterio

The paper defines a core NRF2 gene set from transcriptomic data that predicts drug resistance and poor cancer prognosis across multiple cancer types.

bioRxiv · Apr 20, 2023Cancer Biology

Membrane-Bound O-Acyltransferase 7 (MBOAT7)-Driven Lysophosphatidylinositol (LPI) Acylation in Adipocytes Contributes to Systemic Glucose Homeostasis

W. Massey, V. Varadharajan, R. Banerjee, A. L. Brown, A. J. Horak, R. C. Hohe, E. R. Chan, C. Pan, R. Zhang, D. S. Allende, A. J. Lusis, J. M. Brown

This study shows that MBOAT7 in adipocytes regulates PI homeostasis and contributes to hyperinsulinemia and systemic insulin resistance in mice.

bioRxiv · May 19, 2022 · PreprintBiochemistry