Author

E. T. O'Toole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:development & morphogenesis· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

A. J. Stemm-Wolf· 2 shared C. G. Pearson· 2 shared M. Winey· 2 shared A. D. Junker· 1 shared A. W. J. Soh· 1 shared B. A. Bayless· 1 shared B. L. McCurdy· 1 shared C. E. Jewett· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

A. J. Stemm-Wolf

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Author profile →

4 papers

Recent·Most cited

Trisomy 21 induces pericentrosomal crowding disrupting early stages of primary ciliogenesis and mouse cerebellar development

C. E. Jewett, B. L. McCurdy, E. T. O'Toole, K. S. Given, C. H. Lin, V. Olsen, W. Martin, L. G. Reinholdt, J. M. Espinosa, K. D. Sullivan, W. B. Macklin, R. Prekeris, C. G. Pearson

This study shows that trisomy 21 causes pericentrosomal crowding, disrupting ciliogenesis and leading to neurological deficits in mice.

bioRxiv · Nov 10, 2021Cell Biology

The SON RNA splicing factor is required for intracellular trafficking that promotes centriole assembly

A. J. Stemm-Wolf, E. T. O'Toole, R. M. Sheridan, J. T. Morgan, C. Pearson

This study identifies SON as an RNA splicing factor essential for centriole assembly by regulating CEP131 splicing and expression, which is critical for microtubule trafficking and centrosome function.

bioRxiv · Jan 29, 2021Cell Biology

Tetrahymena Poc5 is a transient basal body component that is important for basal body maturation

W. Heydeck, B. A. Bayless, A. J. Stemm-Wolf, E. T. O'Toole, C. Ozzello, M. Nguyen, M. Winey

This study shows that Tetrahymena Poc5 is essential for basal body maturation, affecting both basal body production and ciliogenesis.

Journal of Cell Science · Jun 4, 2020Peer-reviewedCell Biology

Microtubule glycylation promotes basal body attachment to the cell cortex

A. D. Junker, A. W. J. Soh, E. T. O'Toole, J. B. Meehl, M. Guha, M. Winey, J. E. Honts, J. Gaertig, C. G. Pearson

This study identifies tubulin glycylation as essential for basal body microtubule attachment to the cell cortex, which is critical for ciliary array organization.

bioRxiv · Apr 26, 2019Cell Biology