Author

J. T. Morgan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

J. Rutter· 4 shared J. A. Maschek· 3 shared J. A. Berg· 2 shared J. E. Cox· 2 shared K. Funai· 2 shared S. Fogarty· 2 shared S. Lettlova· 2 shared S. P. Gygi· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersBiochemistry

J. Rutter

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

In vitro formation and extended culture of highly metabolically active and contractile tissues

I. A. Bagdasarian, T. I. Tonmoy, B. H. Park, J. T. Morgan

This study develops porous PDMS molding techniques to improve extended culture of contractile and metabolically active 3D cell cultures, showing increased cell density and maturation with optimized surface treatments and feeding schedules.

bioRxiv · Jul 7, 2023 · PreprintBioengineering

Mitochondrial Phosphatidylethanolamine Directly Regulates UCP1 to Promote Brown Adipose Thermogenesis

J. M. Johnson, A. D. Peterlin, E. Balderas, E. G. Sustarsic, J. A. Maschek, M. J. Lang, A. Jara-Ramos, V. Panic, J. T. Morgan, C. J. Villanueva, A. Sanchez, J. Rutter, I. J. Lodhi, J. E. Cox, K. H. Fisher-Wellman, , K. Funai

This study shows mitochondrial phosphatidylethanolamine directly regulates UCP1 to control thermogenesis in brown adipose tissue.

bioRxiv · Aug 26, 2022 · PreprintBiochemistry

Mitochondrial pyruvate supports lymphoma proliferation by fueling a non-canonical glutamine metabolism pathway

P. Wei, A. J. Bott, A. A. Cluntun, J. T. Morgan, C. N. Cunningham, J. C. Schell, Y. Ouyang, S. B. Ficarro, J. A. Marto, N. N. Danial, R. J. DeBerardinis, J. Rutter

This study identifies a non-canonical glutamine metabolism pathway in DLBCLs where mitochondrial pyruvate supports glutaminolysis and proliferation, particularly in solid extracellular matrix environments.

bioRxiv · Aug 26, 2021 · PreprintCancer Biology

The SON RNA splicing factor is required for intracellular trafficking that promotes centriole assembly

A. J. Stemm-Wolf, E. T. O'Toole, R. M. Sheridan, J. T. Morgan, C. Pearson

This study identifies SON as an RNA splicing factor essential for centriole assembly by regulating CEP131 splicing and expression, which is critical for microtubule trafficking and centrosome function.

bioRxiv · Jan 29, 2021Cell Biology

Msp1/ATAD1 restores mitochondrial function in Zellweger Spectrum Disease

E. Nuebel, J. T. Morgan, S. Fogarty, J. M. Winter, S. Lettlova, J. A. Berg, Y.-C. Chen, C. U. Kidwell, J. A. Maschek, K. J. Clowers, C. Argyriou, L. Chen, I. Wittig, J. E. Cox, M. Roh-Johnson, , J. Rutter

The paper investigates peroxisomal dysfunction in Zellweger Spectrum Disease and shows that overexpressing ATAD1 restores mitochondrial function in patient-derived fibroblasts.

bioRxiv · Sep 19, 2020 · PreprintCell Biology

Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism

S. M. Nowinski, A. Solmonson, S. F. Rusin, J. A. Maschek, C. L. Bensard, S. Fogarty, M.-Y. Jeong, S. Lettlova, J. A. Berg, J. T. Morgan, Y. Ouyang, B. C. Naylor, J. A. Paulo, K. Funai, J. Cox, , J. Rutter

This study shows that mitochondrial fatty acid synthesis (mtFAS) regulates electron transport chain (ETC) complexes and skeletal myoblast differentiation, linking fatty acid synthesis to oxidative metabolism.

bioRxiv · May 9, 2020Biochemistry