Author

E. van Anken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bakunts· 1 shared A. Delaunay-Moisan· 1 shared A. Edelman· 1 shared A. Golec· 1 shared A. Hinzpeter· 1 shared A. Orsi· 1 shared A. Premchandar· 1 shared B. Chevalier· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. Bakunts

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Author profile →

3 papers

Recent·Most cited

Congress of multiple dimers is needed for cross-phosphorylation of IRE1α and its RNase activity

A. Bakunts, A. Orsi, R. Sitia, E. van Anken, M. Vitale

This study shows that IRE1α requires multiple dimers to undergo cross-phosphorylation and activate its RNase activity during ER stress.

bioRxiv · Dec 18, 2023Cell Biology

Keratin 8 is a scaffolding and regulatory protein of ERAD complexes

I. M. Pranke, B. Chevalier, A. Premchandar, N. Baatallah, K. F. Tomaszewski, S. Bitam, D. Tondelier, A. Golec, J. Stolk, G. L. Lukacs, P. S. Hiemstra, M. Dadlez, D. A. Lomas, J. A. Irving, A. Delaunay-Moisan, , A. Edelman

This study shows that Keratin 8 modulates ERAD complexes, enhancing degradation of misfolded proteins like Z-A1AT and F508del-CFTR, and suggests targeting K8 for therapeutic intervention in A1ATD.

bioRxiv · Feb 1, 2022Cell Biology

Repression of Viral Gene Expression and Replication by the Unfolded Protein Response Effector XBP1u

F. Hinte, E. van Anken, B. Tirosh, W. Brune

This study shows that MCMV uses the UPR to regulate its life cycle by activating the IRE1-XBP1 pathway to counteract XBP1u repression of viral gene expression and replication.

bioRxiv · Oct 23, 2019Microbiology

E. van Anken · henhao