Gba1 deletion causes immune hyperactivation and microbial dysbiosis through autophagic defects
Magda Luciana Atilano, Alexander J. Hull, Catalina-Andreea Romila, Mirjam Lisette Adams, Jacob Wildfire, Enric Ureña, Miranda C. Dyson, Jorge Iván Castillo-Quan, Linda Partridge, Kerri J. Kinghorn
This study shows that Gba1 deletion in flies causes immune hyperactivation and microbial dysbiosis, which can be mitigated by microbiome modulation or autophagy stimulation.
PLoS Genetics · Dec 21, 2023Peer-reviewedNeuroscience