Annika Traa

This study shows that impaired methyl recycling in Arabidopsis leads to shifts in sulfur utilization, affecting metabolism, gene methylation, and plant development.

This study shows that reducing mitochondrial superoxide in the intestine extends longevity in worms by improving stress resistance.

This study shows that disrupting the mitochondrial fission gene drp-1 during development extends the lifespan of daf-2 mutants by improving mitochondrial function and stress resistance.

This study shows that overexpressing mitochondrial fission or fusion genes increases lifespan and stress resistance in C. elegans, despite causing mitochondrial fragmentation.

This study shows that disrupting TBC-2 reduces lifespan and stress resistance in long-lived mitochondrial mutants in C. elegans, suggesting a role for endosomal trafficking in mitochondrial dysfunction-related longevity.

The paper examines nine long-lived C. elegans mutants to show a strong correlation between stress resistance and longevity, driven by overlapping genetic pathways.

This study identifies novel genetic targets that reduce mitochondrial fragmentation in a C. elegans model of polyglutamine toxicity, improving movement and lifespan.

This study shows that ATFS-1 activates multiple stress response pathways to increase resistance to exogenous stressors but reduces lifespan when chronically active.