Author

Ethan G. Thompson

Center for Infectious Disease Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel E. ZakiD· 2 shared Fergal J. DuffyiD· 2 shared Thomas J. ScribaiD· 2 shared Andre Gareth LoxtoniD· 1 shared Elizna MaasdorpiD· 1 shared Gerard C. TrompiD· 1 shared Gerhard WalzliD· 1 shared Helena KuivaniemiiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Daniel E. ZakORCID

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2 papers

Recent·Most cited

Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis

Stuart Meier, James A. Seddon, Elizna Maasdorp, Léanie Kleynhans, Nelita du Plessis, Andre Gareth Loxton, Stephanus Theron Malherbe, Daniel E. Zak, Ethan G. Thompson, Fergal J. Duffy, Stefan H. E. Kaufmann, Tom H. M. Ottenhoff, Thomas J. Scriba, Sara Suliman, Jayne S. Sutherland, , Gerard C. Tromp

The paper identifies gene pathways associated with neutrophil and platelet responses that are activated up to six months before TB diagnosis in whole blood.

PLoS ONE · Dec 1, 2022Peer-reviewedGenomics

Multinomial modelling of TB/HIV co-infection yields a robust predictive signature and generates hypotheses about the HIV+TB+ disease state.

Fergal J. Duffy, Ethan G. Thompson, Thomas J. Scriba, Daniel E. Zak

The paper develops a 10-gene random forest signature to predict TB and HIV status and distinguishes TB/HIV co-infection from other conditions with high accuracy.

PLoS ONE · Jul 15, 2019Peer-reviewedSystems Biology