Author

M. Razzaghi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:biophysical modeling· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. Spies· 3 shared M. Honda· 2 shared P. Gaur· 2 shared A. Alp· 1 shared A. C. Straub· 1 shared A. Casey· 1 shared A. Fagunloye· 1 shared A. Stanfield· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBiochemistry

M. Spies

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A double-ring of human RAD52 remodels replication forks restricting fork reversal

M. Honda, M. Razzaghi, P. Gaur, E. Malacaria, G. Marozzi, L. Di Biagi, F. A. Aiello, E. A. Paintsil, A. Stanfield, B. J. Deppe, L. Gakhar, N. J. Schnicker, M. A. Spies, P. Pichierri, M. Spies

The paper shows human RAD52 forms a double-ring structure around stalled replication forks, remodeling them via DNA strand exchange to prevent reversal by SMARCAL1.

bioRxiv · Nov 14, 2023 · PreprintBiochemistry

Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.

L. Hong, d. C. Braden, Y. Zhao, J. J. Skoko, F. Chang, S. R. Woodcock, C. Uvale, A. Casey, K. Wood, S. Salavatore, A. Alp, T. Harkness, A. Fagunloye, M. Razzaghi, A. C. Straub, , C. A. Carola

This paper identifies nitroalkenes that inhibit RAD51-mediated homologous recombination, enhancing DNA damage in triple-negative breast cancer cells and showing potential as anticancer agents.

bioRxiv · Aug 11, 2023Pharmacology & Toxicology

Human hnRNPA1 reorganizes telomere-bound Replication Protein A

S. L. Granger, R. Sharma, V. Kaushik, M. Razzaghi, M. Honda, P. Gaur, D. S. Bhat, S. M. Labenz, J. E. Heinen, B. A. Williams, A. Tabei, M. Wlodarski, E. Antony, M. Spies

The paper shows hnRNPA1 remodels RPA bound to telomeric ssDNA, forming a ternary complex regulated by TERRA.

bioRxiv · May 9, 2023Biophysics