Author

F. J. DeMayo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 5 Cell Biology· 1

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Approach:experimental assay· 6 Organism:mouse· 6 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:gene regulatory network inference· 2 Assay:DNA methylation· 1

Frequent Co-Authors

J. Liu· 3 shared J. P. Lydon· 3 shared C. J. Creighton· 2 shared A. M. Buechlein· 1 shared B. D. Murphy· 1 shared B. Gu· 1 shared C. J. Wilson· 1 shared D. Monsivais· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

J. Liu

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Author profile →

6 papers

Recent·Most cited

Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

S. Vallabhaneni, J. Liu, M. Morel, W. Wang, F. J. Demayo, W. Long

Molecular Oncology · Dec 14, 2021Peer-reviewedCancer Biology

Dependency of LKB1-inactivated lung cancer on aberrant CRTC-CREB activation

X. Zhou, J. W. Li, Z. Chen, W. Ni, X. Li, R. Yang, H. Shen, J. Liu, F. J. DeMayo, J. Lu, F. J. Kaye, L. Wu

This study shows that CRTC-CREB activation drives LKB1-null lung cancer growth and identifies it as a therapeutic target.

bioRxiv · Jan 9, 2021Cancer Biology

Cell-type specific analysis of physiological action of estrogen in mouse oviducts

E. A. McGlade, G. G. Herrera, K. K. Stephens, S. L. Olsen, S. Winuthayanon, J. Guner, S. C. Hewitt, K. S. Korach, F. J. DeMayo, J. P. Lydon, D. Monsivais, W. Winuthayanon

This study investigates how estrogen affects different cell types in mouse oviducts using scRNA-seq and identifies Igf1 as an estrogen-target gene linked to fertility.

bioRxiv · Dec 18, 2020Cell Biology

Pten and Dicer1 loss causes poorly-differentiated endometrial adenocarcinoma in mice

X. Wang, J. Wendel, R. E. Emerson, R. R. Broaddus, C. J. Creighton, D. Rusch, A. M. Buechlein, F. J. DeMayo, J. P. Lydon, S. Hawkins

This paper shows that deleting Pten and Dicer1 in mice leads to poorly-differentiated endometrial adenocarcinoma with molecular features similar to human DICER1-mutant cancers.

bioRxiv · Mar 12, 2020 · PreprintCancer Biology

Constitutive Expression of the Progesterone Receptor Isoforms Promotes Hormone-Dependent Development of Ovarian Neoplasms

M. Wetendorf, R. Li, S.-P. Wu, J. Liu, C. J. Creighton, T. Wang, K. S. Janardhan, C. J. Wilson, R. B. Lanz, B. D. Murphy, J. P. Lydon, F. J. DeMayo

This study shows that overexpression of PGRB promotes ovarian tumor development in mice, while PGRA reduces tumor frequency, highlighting the role of PGR isoforms in hormone-dependent neoplasia.

bioRxiv · Oct 24, 2019Cancer Biology

Super-enhancer impairment is a link between MLL4 inactivated lung tumors and their vulnerability to glycolysis pathway inhibition

H. Alam, M. Tang, M. Maitituoheti, S. S. Dhar, S. Amin, B. Gu, T.-Y. Chen, Y.-H. Lin, J. Chen, F. Muller, F. J. DeMayo, L. Baseler, K. Rai, M. Lee

The paper shows that MLL4 loss in lung cancer promotes glycolysis and that inhibiting glycolysis selectively targets MLL4-mutant lung tumors.

bioRxiv · Dec 28, 2018 · PreprintCancer Biology