Author

R. B. Lanz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. M. Dean· 1 shared B. D. Murphy· 1 shared B. W. O'Malley· 1 shared C. C. Dacso· 1 shared C. J. Creighton· 1 shared C. J. Wilson· 1 shared D. M. Lonard· 1 shared F. J. DeMayo· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. M. Dean

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion

S. J. Han, P. Jain, Y. Gilad, Y. Xia, N. Sung, M. J. Park, A. M. Dean, R. B. Lanz, J. Xu, C. C. Dacso, D. M. Lonard, B. W. O'Malley

This study shows that deleting SRC-3 in regulatory T cells eradicates tumors in mouse models by enhancing antitumor immunity without autoimmune side effects.

bioRxiv · Mar 28, 2023Cancer Biology

Constitutive Expression of the Progesterone Receptor Isoforms Promotes Hormone-Dependent Development of Ovarian Neoplasms

M. Wetendorf, R. Li, S.-P. Wu, J. Liu, C. J. Creighton, T. Wang, K. S. Janardhan, C. J. Wilson, R. B. Lanz, B. D. Murphy, J. P. Lydon, F. J. DeMayo

This study shows that overexpression of PGRB promotes ovarian tumor development in mice, while PGRA reduces tumor frequency, highlighting the role of PGR isoforms in hormone-dependent neoplasia.

bioRxiv · Oct 24, 2019Cancer Biology