Author

F. J. O'Reilly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Rappsilber· 2 shared A. Belsom· 1 shared A. J. R. Heck· 1 shared B. C. Amaral· 1 shared C. Borchers· 1 shared C. Emanuelsson· 1 shared C. Gutierrez· 1 shared C. Haupt· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

J. Rappsilber

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3 papers

Recent·Most cited

AI-guided cryo-EM probes a thermophilic cell-free system with succinyl-coA manufacturing capability

I. Skalidis, F. L. Kyrilis, C. Tueting, F. Hamdi, T. K. Traeger, J. Belapure, G. Hause, M. Fratini, F. J. O'Reilly, I. Heilmann, J. Rappsilber, P. L. Kastritis

The paper characterizes a thermophilic cell-free system producing succinyl-CoA using cryo-EM and biochemical methods, revealing its molecular structure and functional organization.

bioRxiv · Oct 8, 2022 · PreprintBiochemistry

An integrated workflow for cross-linking/mass spectrometry

M. L. Mendes, L. Fischer, Z. A. Chen, M. Barbon, F. J. O'Reilly, S. Giese, M. Bohlke-Schneider, A. Belsom, T. Dau, C. W. Combe, M. Graham, M. R. Eisele, W. Baumeister, C. Speck, J. Rappsilber

The paper introduces a workflow combining sequential digestion and Xi software to improve cross-linking mass spectrometry detection of protein interactions.

bioRxiv · Mar 6, 2019Biochemistry

Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines

C. Iacobucci, C. Piotrowski, R. Aebersold, B. C. Amaral, P. Andrews, C. Borchers, N. I. Brodie, J. E. Bruce, S. Chaignepain, J. D. Chavez, S. Claverol, J. Cox, G. Degliesposti, M. Q. Dong, N. Edinger, , Rand

This paper summarizes current XL-MS practices, compares strategies, and proposes common protocols to establish best practice guidelines for accurate and reproducible results.

bioRxiv · Sep 26, 2018 · PreprintBiochemistry