Author

G. Degliesposti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

J. M. Skehel· 2 shared V. J. Planelles-Herrero· 2 shared A. Bittleston· 1 shared A. Galindo· 1 shared B. Daum· 1 shared C. Janke· 1 shared C. Prodromou· 1 shared D. Bjorklund· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

J. M. Skehel

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Author profile →

4 papers

Recent·Most cited

Elongator is a microtubule polymerase selective for poly-glutamylated tubulin

V. J. Planelles-Herrero, M. Genova, A. Bittleston, K. E. McNally, G. Degliesposti, M. M. Magiera, C. Janke, E. Derivery

This paper identifies Elongator's role in stabilizing microtubules by selectively binding polyglutamylated tubulin, contributing to cell fate determination during asymmetric division.

bioRxiv · May 10, 2023 · PreprintBiochemistry

A cryo-EM structure of metazoan TRAPPIII, the multisubunit complex that activates the GTPase Rab1

A. Galindo, V. J. Planelles-Herrero, G. Degliesposti, S. Munro

The paper presents a cryo-EM structure of Drosophila TRAPPIII, revealing how its large subunits interact with the core to regulate Rab1 activation and providing insights into its evolutionary relationship with TRAPPII.

bioRxiv · Dec 17, 2020Cell Biology

Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone

M. Pal, H. Munoz-Hernandez, D. Bjorklund, L. Zhou, G. Degliesposti, J. M. Skehel, E. L. Hesketh, R. F. Thompson, L. H. Pearl, O. Llorca, C. Prodromou

The paper determines the cryo-EM structure of the human R2TP-TTT complex and shows how TTT recruits TOR to R2TP while regulating its chaperone activity.

bioRxiv · Nov 9, 2020Biochemistry

Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis

S. Alvira-de-Celis, D. W. Watkins, L. Troman, W. J. Allen, J. Lorriman, G. Degliesposti, E. J. Cohen, M. J. Beeby, B. Daum, V. A. M. Gold, J. M. Skehel, I. Collinson

The paper investigates the inter-membrane association between Sec and BAM translocons in bacterial outer-membrane biogenesis, showing their interaction ensures efficient OMP maturation.

bioRxiv · Jul 2, 2020Biochemistry