Author

C. Borchers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

E. Petrotchenko· 2 shared A. Carles· 1 shared A. Hernnandez Corchado· 1 shared A. J. R. Heck· 1 shared A. Jahani-asl· 1 shared A. Martinez de Paz· 1 shared A. Velazquez-Campoy· 1 shared B. C. Amaral· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

E. Petrotchenko

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4 papers

Recent·Most cited

An effective C. elegans CRISPR training module for high school and undergraduate summer research experiences in molecular biology

C. Herrera-Sandoval, C. Borchers, S. T. Aoki

This study develops an eight-week CRISPR training program for high school and undergraduate students using C. elegans, showing improved molecular biology skills and enthusiasm.

bioRxiv · Sep 13, 2023 · PreprintScientific Communication & Education

The E3 Ubiquitin Ligase Nedd4L Acts as a Checkpoint Against Activation in Quiescent Muscle Stem Cells

D. Blackburn, K. Sahinyan, A. Hernnandez Corchado, F. Lazure, V. Richard, L. Raco, R. Zahedi, C. Borchers, C. Lepper, H. Kawabe, A. Jahani-asl, H. S. Najafabadi, V. D. Soleimani

This study identifies the PAX7/NEDD4L axis as a checkpoint regulating quiescence in muscle stem cells, showing that Nedd4L deletion impairs quiescence and promotes activation.

bioRxiv · May 10, 2023 · PreprintCell Biology

Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines

C. Iacobucci, C. Piotrowski, R. Aebersold, B. C. Amaral, P. Andrews, C. Borchers, N. I. Brodie, J. E. Bruce, S. Chaignepain, J. D. Chavez, S. Claverol, J. Cox, G. Degliesposti, M. Q. Dong, N. Edinger, , Rand

This paper summarizes current XL-MS practices, compares strategies, and proposes common protocols to establish best practice guidelines for accurate and reproducible results.

bioRxiv · Sep 26, 2018 · PreprintBiochemistry

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

A. Martinez de Paz, L. Khajavi, H. Martin, R. Claveria-Gimeno, S. tom Dieck, M. S. Cheema, J. V. Sanchez-Mut, M. Moksa, A. Carles, N. Brodie, T. I. Sheikh, M. Freeman, E. Petrotchenko, C. Borchers, E. Schuman, , J. Ausio

This study compares MeCP2-E1 and E2 isoforms, showing differences in DNA binding, protein interactions, and dynamic behavior, with implications for their functional roles in chromatin regulation.

bioRxiv · Aug 17, 2018Biochemistry