Author

D. Moreau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

S. Vossio· 3 shared F. Vacca· 2 shared J. Gruenberg· 2 shared J. Paz Montoya· 2 shared M. Moniatte· 2 shared A. Colaco· 1 shared C. C. Scott· 1 shared C. Ferguson· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

S. Vossio

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Discovery of anti-infective compounds against Mycobacterium marinum after biotransformation of simple natural stilbene scaffolds by a fungal secretome

N. Hanna, T. Soldati, J. Nitschke, R. Huber, S. Vossio, D. Moreau, L. Marcourt, K. Gindro, E. F. Queiroz

This study identifies trans-δ-viniferins as promising anti-infective scaffolds against Mycobacterium marinum using a Dictyostelium discoideum infection model and natural product derivatives.

bioRxiv · Apr 18, 2024 · PreprintMicrobiology

Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice

D. Moreau, F. Vacca, S. Vossio, C. C. Scott, A. Colaco, J. Paz Montoya, C. Ferguson, M. Damme, M. Moniatte, R. G. Parton, F. M. Platt, J. Gruenberg

The paper identifies thioperamide as a drug that increases lysobisphosphatidic acid (LBPA) levels, reducing cholesterol overload in Niemann-Pick type C cells and mice.

bioRxiv · Mar 8, 2019Cell Biology

Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells

F. Vacca, S. Vossio, V. Mercier, D. Moreau, S. Johnson, J. Paz Montoya, M. Moniatte, J. Gruenberg

This study shows cyclodextrin induces endo-lysosome secretion in Niemann-Pick type C cells via MCOLN1, reducing cholesterol storage.

bioRxiv · Aug 27, 2018Cell Biology