Author

Francesca Sciarretta

University of Rome Tor Vergata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Andrea Ninni· 2 shared Alessandro Sgambato· 1 shared Antonio GiordanoiD· 1 shared Antonio M.A. Miranda· 1 shared Beiyan ZhouiD· 1 shared Christophe LachaudiD· 1 shared Claudia Di BiagioiD· 1 shared Clément CochainiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

Andrea Ninni

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Non-canonical TERT function mitigates adipose tissue inflammation in obesity by modulating stem cell-macrophage communication and macrophage states

Laura Braud, Andrea Ninni, Antonio M.A. Miranda, Émilie Baudelet, Julien Vernerey, Marina Villaverde, Francesca Sciarretta, Manuel Bernabe, Léa Girondier, Ilaria Elia, Jesús Gil, Stéphane Audebert, Jean‐Marc Brondello, Christophe Lachaud, Will Scott, , Vincent Géli

This study shows that TERT expression in adipose tissue reduces inflammation and improves metabolism in obesity by altering macrophage states and stem cell-macrophage communication.

bioRxiv · Dec 18, 2025 · PreprintPhysiology

MACanalyzeR: scRNA-seq Analysis Tool Reveals PPARγHI Lipid-Associated Macrophages Facilitate Thermogenic Expansion in BAT

Andrea Ninni, Fabio Zaccaria, Luca Verteramo, Francesca Sciarretta, Loreana Sanches Silveira, José Cesar Rosa Neto, Simone Carotti, Lorenzo Nevi, Paolo Grumati, Satish Patel, Giulia Carrera, Alessandro Sgambato, Donatella Lucchetti, Filomena Colella, Ilenia Severi, , Daniele Lettieri‐Barbato

The paper introduces MACanalyzeR, a scRNA-seq tool, to identify PPARγ-high lipid-associated macrophages in BAT that support thermogenic expansion.

Nature Communications · May 31, 2025Peer-reviewedPhysiology