Author

G. A. Heinz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

M.-F. Mashreghi· 5 shared P. Durek· 5 shared A. Radbruch· 4 shared H.-D. Chang· 4 shared F. Heinrich· 3 shared A. Diefenbach· 2 shared K. Lehmann· 2 shared P. Enghard· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersImmunology

M.-F. Mashreghi

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota

I. Roewekamp, L. Maschirow, A. Rabes, F. Fiocca Vernengo, G. A. Heinz, M.-F. Mashreghi, S. Caesar, M. Milek, A. Fagundes, S.-M. Wienhold, G. Nouailles, L. Yao, D. Bruder, J. Boehme, M. Puzianowska-Kuznicka, , B. Opitz

This study shows IL-33 reduces IL-22 production in innate lymphoid cells, increasing resistance to Streptococcus pneumoniae infection, and links genetic variation in IL-33 signaling to human pneumonia.

bioRxiv · Jul 19, 2023Immunology

MicroRNA-221/222-expression in HSC and MPP safeguards their quiescence and multipotency by downregulating stress-independent and dependent expression of IEG and of several myelo/granulopoiesis-enhancing target genes.

P. K. Jani, G. Petkau, Y. Kawano, U. Klemm, G. M. Guerra, G. A. Heinz, F. Heinrich, P. Durek, M.-F. Mashreghi, F. Melchers

This study shows that miR-221/222 in HSC and MPP maintains quiescence and multipotency by suppressing IEGs and myelo/granulopoiesis genes, with implications for improving bone marrow transplants.

bioRxiv · Jan 30, 2023 · PreprintImmunology

Induction of cross-reactive antibody responses against the RBD domain of the spike protein of SARS-CoV-2 by commensal microbiota

J. Ninnemann, L. Budzinski, M. Bondareva, M. Witkowski, S. Angermair, J. Kreye, P. Durek, M. Reincke, E. Sanchez-Sendin, S. Yilmaz, T. Sempert, G. A. Heinz, C. Tizian, M. Raftery, G. Schoenrich, , A. Kruglov

This study identifies commensal bacteria that induce cross-reactive anti-RBD IgA antibodies against SARS-CoV-2 in humans and mice.

bioRxiv · Aug 8, 2021 · PreprintMicrobiology

Mobilization of tissue-resident memory CD4+ T lymphocytes and their contribution to a systemic secondary immune reaction

C. c. Cendon, W. Du, P. Durek, T. Alexander, L. Serene, T. Lai, A. R. Schulz, A. Rao, G. A. Heinz, A.- L. Stefanski, A. Bruns, K. Siewert, T. Doerner, H.-D. Chang, H. D. Volk, , J. Dong

The paper shows that tissue-resident memory CD4+ T cells mobilize into the blood after vaccination and contribute to systemic secondary immune responses.

bioRxiv · Apr 2, 2020Immunology

Antigen-driven PD1+Tox+Eomes+ and PD1+Tox+BHLHE40+ synovial T lymphocytes regulate chronic inflammation in situ

P. Maschmeyer, G. A. Heinz, C. Skopnik, L. Lutter, A. Mazzoni, F. Heinrich, S. L. von Stuckrad, L. E. Wirth, C. L. Tran, R. Riedel, K. Lehmann, I. Sakwa, R. Cimaz, F. Giudici, M. A. Mall, , M.-F. Mashreghi

The paper identifies distinct subpopulations of synovial T lymphocytes in JIA patients using single-cell RNA-sequencing and shows their roles in regulating chronic inflammation.

bioRxiv · Dec 27, 2019 · PreprintImmunology

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

R. Riedel, R. K. Addo, M. Ferreira-Gomes, G. A. Heinz, F. Heinrich, J. Kummer, V. Greiff, D. Schulz, C. Klaeden, R. Cornelis, U. Menzel, S. Kröger, U. Stervbo, R. Köhler, C. Haftmann, , A. Radbruch

The paper identifies discrete populations of isotype-switched memory B cells in murine spleen and bone marrow, with distinct locations and characteristics.

bioRxiv · Oct 31, 2019Immunology