Author

U. Klemm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:imaging· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. C. Stiel· 2 shared V. Ntziachristos· 2 shared A. Bluetke· 1 shared A. Feuchtinger· 1 shared C. Chumduri· 1 shared F. Heinrich· 1 shared F. Melchers· 1 shared G. A. Heinz· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

A. C. Stiel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MicroRNA-221/222-expression in HSC and MPP safeguards their quiescence and multipotency by downregulating stress-independent and dependent expression of IEG and of several myelo/granulopoiesis-enhancing target genes.

P. K. Jani, G. Petkau, Y. Kawano, U. Klemm, G. M. Guerra, G. A. Heinz, F. Heinrich, P. Durek, M.-F. Mashreghi, F. Melchers

This study shows that miR-221/222 in HSC and MPP maintains quiescence and multipotency by suppressing IEGs and myelo/granulopoiesis genes, with implications for improving bone marrow transplants.

bioRxiv · Jan 30, 2023 · PreprintImmunology

Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice

S. Huang, A. Bluetke, A. Feuchtinger, U. Klemm, R. Z. Tom, S. Hofmann, A. C. Stiel, V. Ntziachristos

This study uses MSOT to non-invasively visualize lipid accumulation in mice with NAFLD, showing its potential for monitoring hepatic steatosis without contrast agents.

bioRxiv · Dec 17, 2020Bioengineering

Multiplexed whole animal imaging with reversibly switchable optoacoustic proteins

K. Mishra, M. Stankevych, J. P. Fuenzalida-Werner, S. Grassmann, V. Gujrati, U. Klemm, V. R. Buchholz, V. Ntziachristos, A. C. Stiel

The paper introduces two photochromic proteins for multiplexed in vivo optoacoustic imaging and develops software to enable temporal signal unmixing in commercial systems.

bioRxiv · Feb 1, 2020Biochemistry

Transition of Wnt signaling microenvironment delineates the squamo-columnar junction and emergence of squamous metaplasia of the cervix

C. Chumduri, R. K. Gurumurthy, H. Berger, S. Koster, V. Brinkmann, U. Klemm, H.-J. Mollenkopf, H. Herbst, M. Mangler, T. F. Meyer

The paper identifies that Wnt signaling dynamics in the stroma regulate the squamo-columnar junction and the emergence of squamous metaplasia in the cervix, without a localized stem cell population at the boundary.

bioRxiv · Oct 16, 2018Cancer Biology