An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei
G. Bandini, S. Damerow, M. L. Sempaio Güther, H. Guo, A. Mehlert, S. M. Beverley, M. A. J. Ferguson
This study identifies TbFUT1 as an essential mitochondrial fucosyltransferase in Trypanosoma brucei, critical for both bloodstream and procyclic forms and potentially therapeutically relevant across trypanosomatids.
bioRxiv · May 11, 2021Microbiology