Author

G. de Bree

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Organism:virus· 1

Frequent Co-Authors

G. Vidarsson· 2 shared M. van Gils· 2 shared P. Brouwer· 2 shared R. Sanders· 2 shared T. Caniels· 2 shared A. Aartse· 1 shared A. Bentlage· 1 shared A. Neele· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

G. Vidarsson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antibodies against SARS-CoV-2 control complement-induced inflammatory responses to SARS-CoV-2

M. Bermejo-Jambrina, L. E. H. van der Donk, J. L. van Hamme, D. Wilflingseder, G. de Bree, M. Prins, M. de Jong, P. Nieuwkerk, M. J. van Gils, N. A. Kootstra, T. Geijtenbeek

This study shows that antibodies against SARS-CoV-2 reduce complement-induced inflammation, suggesting a role for complement in immune activation and antibody-mediated immune regulation.

bioRxiv · May 29, 2023 · PreprintImmunology

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

W. Hoepel, H.-J. Chen, S. Allahverdiyeva, X. Manz, J. Aman, P. Bonta, P. Brouwer, S. de Taeye, T. Caniels, K. van der Straten, K. Golebski, G. Griffith, R. Jonkers, M. Larsen, F. Linty, , J. den Dunnen

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients induces hyper-inflammatory responses in macrophages, leading to endothelial barrier breakdown and microvascular thrombosis.

bioRxiv · Jul 13, 2020Immunology

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

P. Brouwer, T. Caniels, K. van Straten, J. Snitselaar, Y. Aldon, S. Bangaru, J. Torres, N. Okba, M. Claireaux, G. Kerster, A. Bentlage, M. van Haaren, D. Guerra, J. Burger, E. Schermer, , M. van Gils

This study isolates potent neutralizing antibodies from COVID-19 patients that target multiple sites on the SARS-CoV-2 spike protein, offering insights for vaccine design and therapeutic development.

bioRxiv · May 12, 2020Microbiology