Author

G. Dowgier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. E. Firth· 1 shared A. H. Patel· 1 shared A. Hobbs· 1 shared A.-K. Reuschl· 1 shared B. G. Hale· 1 shared B. Williams· 1 shared C. Jolly· 1 shared C. Lefevre· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. E. Firth

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Accurate evaluation of live-virus microneutralisation for SARS-CoV-2 variant JN.1

G. Dowgier, A. Hobbs, D. Greenwood, M. Shawe-Taylor, P. Stevenson-Leggett, J. Bazire, R. Penn, R. Harvey, V. Libri, G. Kassiotis, S. Gamblin, N. S. Lewis, B. Williams, C. Swanton, S. Gandhi, , M. Y. Wu

The paper evaluates neutralising antibody titres against SARS-CoV-2 variant JN.1 using live-virus microneutralisation assays in vaccinated individuals, finding higher titres in monovalent vaccine recipients.

bioRxiv · Apr 17, 2024 · PreprintMicrobiology

Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants

A.-K. Reuschl, L. G. Thorne, M. X. V. Whelan, R. Ragazzini, W. Furnon, V. M. Cowton, G. de Lorenzo, D. Mesner, J. E. Turner, G. Dowgier, N. Bogoda, P. Bonfanti, M. Palmarini, A. H. Patel, C. Jolly, G. J. Towers

This study shows that later Omicron subvariants of SARS-CoV-2, such as BA.4 and BA.5, have evolved enhanced innate immune suppression compared to earlier subvariants like BA.1 and BA.2.

bioRxiv · Jul 12, 2022Microbiology

Manipulation of the unfolded protein response: a pharmacological strategy against coronavirus infection

L. Echavarria-Consuegra, G. M. Cook, I. Busnadiego, C. Lefevre, S. Keep, K. Brown, N. Doyle, G. Dowgier, K. Franaszek, N. A. Moore, S. G. Siddell, E. Bickerton, B. G. Hale, A. E. Firth, I. Brierley, N. Irigoyen

This paper investigates the unfolded protein response (UPR) in coronavirus infection and shows that pharmacological inhibition of the UPR significantly reduces viral replication.

bioRxiv · Mar 19, 2021Microbiology