Author

G. Fell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Anderson· 1 shared A. C. Palmer· 1 shared A. Madi· 1 shared A. Regev· 1 shared B. M. Alexander· 1 shared D. Mangani· 1 shared D. Neuberg· 1 shared D. Plana· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. C. Anderson

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2 papers

Recent·Most cited

Cancer patient survival can be accurately parameterized, revealing time-dependent therapeutic effects and doubling the precision of small trials

D. Plana, G. Fell, B. M. Alexander, A. C. Palmer, P. K. Sorger

The paper imputes survival data from oncology trials and shows that using Weibull distributions improves trial precision and reveals time-dependent therapeutic effects in immune checkpoint inhibitor trials.

bioRxiv · May 14, 2021Cancer Biology

An endogenous glucocorticoid-cytokine signaling circuit promotes CD8+ T cell dysfunction in the tumor microenvironment

N. Acharya, A. Madi, H. Zhang, M. Klapholz, E. Christian, K. O. Dixon, G. Fell, K. Tooley, D. Mangani, J. Xia, M. Singer, D. Neuberg, O. Rozenblatt-Rosen, A. Regev, V. K. Kuchroo, A. C. Anderson

This study identifies a glucocorticoid-cytokine signaling circuit in the tumor microenvironment that promotes CD8+ T cell dysfunction and correlates with poor response to checkpoint blockade in melanoma.

bioRxiv · Oct 10, 2019 · PreprintImmunology